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Exelon is a selective acetylcholinesterase inhibitor used for the treatment of Alzheimer’s disease. Slowing a destruction of acetylcholine, Exelon selectively increases its amount in the brain and improves the nervous transfer.
Due to the development of Alzheimer’s disease, the pathological changes happen in the cholinergic nervous transfer. Due to this, a significant reduction of the cognitive functions is observed, and this leads to dimension.
The use of Exelon improves a general physical activity, reduces an intensity of the diseases of the central nervous system, improves memory and other cognitive functions. A medical effect is observed starting from the 12 week of the treatment and is kept within entire period of the drug use.
The action of Exelon is reversible, and therefore patients are prescribed this medicine on a regular basis. After the end of the use, a destruction of acetylcholine may be restored, so that the symptoms of the Alzheimer’s disease may grow.
In what dose is Exelon used?
Exelon is produced in tablets for the oral use. They should be used 2 times per day starting from the minimal dose and gradually increasing a working daily dose. An induced dose of Exelon is 1,5 mg 2 times per day. If the side effects are not detected within 2 weeks, and the treatment goes as planned, a dose is gradually increased.
A one-time dose of Exelon is increased every 2 weeks by 1,5 mg. It means, that it is necessary to take 3 mg 2 times per day in 2 weeks after the started treatment, then in 2 weeks, 4,5 mg is used per day, and so on. The maximal daily dose of Exelon is 12 mg. To achieve the best therapeutic effect a dose is kept on the maximally good level.
- A cholinergic stimulation may increase a secretion of hydrochloric acid in the stomach, and therefore patients with ulcer of stomach and duodenum should be careful
- The simultaneous use of Exelon with other cholinomimetics is not recommended
- You should not take Exelon during pregnancy
- Stop breast-feeding during the treatment
If you have just started taking Exelon, you should be ready for some side effects: increased fatigue, asthenia, dizziness, headache, drowsiness, agitation, nausea, vomiting, diarrhea, abdominal pain.
The side effects usually pass. But if negative symptoms cause physiological or psychological discomfort, a dose may be temporarily reduced.
In rare cases, it is recommended to stop the use of the drug for 2-3 days and wait till the side effects are completely gone.
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