Bystolic is a non-selective beta-blocker which has a fluent vasodilating action. It is used in the cardiological practice to treat the cardiovascular diseases. Bystolic contains Nebivolol which provides a broad action.
Bystolic relieves the treatment of the arterial hypertension, all forms of the heart failure, and ischemic heart disease. It lowers a frequency of the heart beats and lowers the blood pressure both at rest and during physical activity. Due to this, a load to the cardia muscle is reduced, and a normal function of the vessels and heart is kept. Bystolic causes an antianginal effect in patients with ischemic heart disease.
The active ingredients of Bystolic are quickly absorbed from the gastro-intestinal tract and go to the systemic blood flow. The maximal concentration of Nebivolol in the blood may occur in 20-30 hours depending on the speed of the metabolic processes in the body. But in spite of a good bioavailability, the action of Bystolic occurs slowly. A stable hypotensive effect occurs only in 1-2 weeks after the started treatment, and the maximal therapeutic effect occurs only in 4 weeks. Therefore, Bystolic does not do for a one-time application during hypertonic crisis and unstable heartbeat.
Bystolic may be used on a regular basis in the treatment of such diseases as hypertension, chronic heart failure, ischemic heart disease to prevent acute attacks of angina.
In what dose is Bystolic used?
A positive effect occurs only during the systemic treatment. The pills are used at the same time, once per day, with enough water. The treatment is started from low doses of 2,5-5 mg per day. Due to the successful adaptation to Nebivolol and absence of the side effects, a dose may be increased up to 10 mg per day.
Patients over 65 years old should take not more than 5 mg per day. If chronic heart failure, an induced dose of Bystolic should be 1,25 mg. If positive dynamics is observed in the treatment, a daily dose may be increased up to 2,5 mg per day in 2-3 weeks. This way, it is possible to gradually increase the dose up to 5-10 mg.
- If a patient has side effects due to the increased dose within 1-2 days, a dose should be lowered. If the side effects cause a severe discomfort, the use of Bystolic is completely stopped
- Bystolic is contraindicated during bradycardia, bronchial asthma or obstructive airways disease, myasthenia gravis, cardiogenic shock, acute heart failure, hypotension, depression
- Bystolic may be used during pregnancy only under doctor’s supervision
During the studies, severe side effects have not been recorded. Usually the use of Bystolic is accompanied by short-term headache or dizziness, dry mouth, dyspepsia, and bronchospasm.
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